Blood Serum Plasma Pepsinogen I Pepsinogen Ⅱ Test For Stomach Cancer

Description

Pepsinogen is the precursor of pepsin and can be classified into PG I and PG II. PG I is secreted by chief cells of gastric fundus gland and mucous neck cells. PG II is secreted by chief cells and mucous neck cells. PG synthesized by gastric mucosa mostly enters gastric cavity. Only a small amount (about 1%) enters the blood. Serum PG concentration can reflect its secretion level. When mucosal atrophy of gastric body is predominant, the quantity of parietal cells and chief cells decreases. Pyloric gland has no chief cell and mucous neck cell. Therefore, PG I secretion significantly decreases and serum PG I concentration also declines. PG II is mainly originated from gastric antrum and duodenum. Serum PG II concentration is normal or increases slightly. PG I/PG II ratio (PGR) is a clinical commonly used serological diagnosis and treatment indicator and can reflect the changes of gastric status. Therefore, determination of serum PG I and PG II can assist diagnosis of early gastric diseases.

Benefits

• Non-invasive: The pepsinogen test is a non-invasive method of testing for gastric function disorder. It does not require an endoscopy or other invasive procedures, which reduces patient discomfort and risk of complications.

• Early detection: Early detection of gastritis, H. pylori infection, and gastric cancer.

• Easy operation: The serum pepsinogen test support blood sample, which makes the test easier to perform.

Product Specifications

※ Refer to Package Insert for additional product information.

Product Performance

Applications

• Outpatient Emergency Laboratory

• Clinical Departments

• Community Hospital

• Laboratory Departments

• Health Management Center

• Clinic

Certifications