Clinical Application of Calprotectin Testing in Functional Gastrointestinal Disorders

01-03-2024

Calprotectin testing has been being used gradually in clinical application in the field of functional gastrointestinal disorders (FGIDs). A recent study has demonstrated the potential of calprotectin as a diagnostic and monitoring tool for FGIDs, such as irritable bowel syndrome (IBS).


FGIDs are characterized by chronic or recurrent gastrointestinal symptoms without structural or biochemical abnormalities. Diagnosis of FGIDs has traditionally relied on symptom-based criteria, which can be subjective and imprecise. Calprotectin testing offers an objective biomarker to aid in the assessment of these disorders. The study revealed that elevated levels of calprotectin are associated with increased disease severity and symptom burden in patients with FGIDs. It indicated that calprotectin may serve as a useful adjunct to differentiate between FGIDs and organic gastrointestinal diseases, leading to more accurate diagnoses and appropriate management strategies.


The diagnostic kit for calprotectin independently developed and produced by Xiamen Wiz Biotech Co., Ltd. has high sensitivity and strong specificity. The clinical application of calprotectin testing in FGIDs is expected to improve the diagnostic accuracy and patient outcomes, and reduce healthcare costs in unnecessary investigations. Further studies and guidelines to bring the calprotectin testing into clinical practice are necessary in order to play its potential role in the management of FGIDs.


Xiamen Wiz Biotech Co., Ltd is a high-tech company engaging in the research and development, production and sales of rapid diagnostic reagents and instruments. Focusing on technological innovation, WIZBIOTECH develops POCT testing reagents and instruments, and takes advantage of existing channels to expand more medical markets, with a view to contribute more in the field of rapid diagnostic POCT. 

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