Gastrin-17: A Key Hormone in Digestion and Its Diagnostic Importance

21-05-2025

Functions of Gastrin-17

The primary role of gastrin-17 is to promote gastric acid secretion, which is essential for:

  • Protein digestion: HCl denatures proteins, making them more accessible to digestive enzymes like pepsin.

  • Pathogen defense: The acidic environment kills harmful bacteria and other microorganisms ingested with food.

  • Nutrient absorption: Gastric acid aids in the absorption of minerals such as iron and calcium.

Beyond acid regulation, gastrin-17 also influences gastric motility, ensuring proper mixing and movement of food through the stomach and into the small intestine. Additionally, it supports mucosal cell growth and repair, maintaining the integrity of the stomach lining.

Clinical Significance of Gastrin-17 Levels

Abnormal gastrin-17 levels can indicate various gastrointestinal disorders:

  • Elevated levels may suggest hypergastrinemia, often seen in conditions such as:

    • Chronic gastritis (especially Helicobacter pylori infections)

    • Peptic ulcers (due to excessive acid production)

    • Zollinger-Ellison syndrome (a rare condition involving gastrin-secreting tumors)

  • Low levels may indicate atrophic gastritis, where the stomach lining is damaged, reducing G cell function and acid secretion. This condition is linked to an increased risk of gastric cancer and vitamin B12 deficiency (pernicious anemia).

The Role of Gastrin-17 Rapid Test Kits

Traditional gastrin testing methods, such as ELISA or radioimmunoassay, can be time-consuming and require specialized laboratory equipment. Gastrin-17 rapid test kits offer a faster, more accessible alternative, enabling early diagnosis and timely treatment decisions. These kits measure gastrin-17 levels in blood serum or plasma, providing results within minutes.

Key advantages include:
✔ Speed: Results in 15 minutes, allowing for immediate clinical assessment.
✔ High sensitivity & accuracy: Reliable detection of abnormal gastrin levels, aiding in the diagnosis of gastric disorders.
✔ Versatility: Gastrin-17 rapid test kits suitable for hospitals, emergency rooms, clinics, and even self-monitoring in high-risk patients.

Wizbiotech’s Gastrin-17 Rapid Test Kit

Wizbiotech’s Blood Serum Plasma Gastric Hormone Gastrin-17 Test is a cutting-edge diagnostic tool designed for quick, in vitro qualitative detection of gastrin-related abnormalities. Its features include:

  • Rapid detection: Gastrin-17 rapid test kits delivers results in just 15 minutes.

  • No additional instruments needed: Simplifies testing in resource-limited settings.

  • High accuracy: Ensures reliable screening for gastritis, ulcers, and other stomach diseases.

  • Broad application: Gastrin-17 rapid test kits ideal for hospital labs, emergency departments, blood centers, and public health screenings.

Conclusion

Gastrin-17 is a crucial hormone for digestive health, and its levels serve as important biomarkers for various gastric disorders. With the advent of rapid test kits, healthcare providers can now diagnose and manage conditions like gastritis, ulcers, and Zollinger-Ellison syndrome more efficiently. Wizbiotech’s Blood Serum Plasma Gastric Hormone Gastrin-17 Test exemplifies innovation in point-of-care diagnostics, offering a fast, accurate, and user-friendly solution for improving gastrointestinal health outcomes.


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